Went to Marsden with my husband yesterday who was diagnosed with stage stage 4 T3 N2 M1c in March, started Keytruda in April, first scan showed a good response, lymph nodes shrinking & cancer stable & cyberknife to brain excellent response, just a dot appearing.

Had 2nd scan in August very anxious as always, I knew the results were in & stupidly thought there would have a call to day come in sooner as things have progressed. But no, we turned up yesterday for pre treatment bloods etc as keytruda due today, to be called in the room to see onco, as normal. After loads of questions, how are you, any cough, symptoms etc she then dropped the bomb shell. Unfortunately the cancers progressed, the lung tumour as grown from 5cm to 7cm & bone met is 4cm, doesnt know how much thats grown as she had no comparison. The cyberknife to brain as had excellent response, but sadly all we heard was progressed.

So keytruda stopped & next wk Pemetrexed & carboplatin ( chemo) every 3 wks, along with Zometa for bones.

I think one of these chemos is a 4 cycle run only. TBH its all a blur. I've cried so much, my husband wont talk about it at all.

Because its chemo its terrifying. Keytruda was every 6 wks but just a few side affects fatigue & nausea.

As anyone been on this chemo & can give an idea of how bad it is? My husband as no symptoms apart from knee pain, which they now thinks related to the keytruda & causing an osteoarthritis flare up.

So scared shocked.....is this basically the end in sight. I cant eat anything, I look at my husband & cry. I cant put into words how I feel, so I hate to think how he feels.

So please if anyone as any advice or as been through this can you let me know plz. We were actually going to ask onco about going away & never even mentioned it after the news...

Thank you for reading...