I am interested in possible clinical trials available.

Also the possibility of immunotherapy when  pMMR not dMMR. 

My wife has stage 3 endometrial cancer. She is in her 5th (of 6) cycle of chemo - paclitaxel and Carboplatin 4 hours of cocktails. Before chemo her tumour was too big for surgery and CA125 1699.  After 3 cycles and CT scan her CA125 was down to 101 and the CT scan showed tumour had shrunk 'considerably'. She has just finished her 5th cycle and CA125 is down to 32.  We had feedback from nurse yesterday that based on results of CT scan (which was after 3 cycles of chemo) they will still not operate and have asked for another CT scan and MRI with the suggestion of radiotherapy.  What would the MRI be for? And I wonder if after the full 6 cycles is the tumour  likely to shrink more or does the impact of the chemo cocktail slow down after three cycles?