For my bowel cancer, I had radio and oral Chemo every day for 5 weeks. As I remember, the Radio side affects built up but the Chemo was pretty instant. By the last week, I ended up for a couple of nights on the ward as I was as done in as I could be. I think that was my lowest point. I didn't finish the last week of Chemo, but did complete Radio. I had no energy, was mentally down and generally just felt awful.

So for me, what your husband is going through sounds pretty 'normal'.  The good news is, a) it did shrink my large tumour enough to operate and remove it, I soon made a full recovery and built strength up again, ready for the op. I think I finished Chemo/Radio at the start of November and By Christmas day I was fitter than I'd every been!

Everyone is different though I'd speak to your oncologist and the team and ask for advice - and anything that can reduce side affects.

Thank you, that's very reassuring. Brilliant that the cancer has gone.

Yeah, the effects of chemo tend to be accumulative, meaning it's not uncommon for people to breeze through the first couple or so treatments, relatively speaking. When my wife was undergoing chemo for BC, I initially thought the chemo stories were overblown, and things weren't as grim as some people made them out to be. Come her 4th treatment, we saw the reality of chemo. The side effects began to ramp up a little after her 3rd dose of treatment.Her last 2 chemo treatments nearly killed her. She landed in hospital each time for days on end.