At a loss - will my mum's treatment for advanced bladder cancer still work if she's unwell? She's currently dehydrated and suffering from lack of appetite

My mum has been diagnosed with metastatic bladder cancer. She has mets on her lungs, kidney, liver and lymph nodes. She has had 3 rounds of Padcev and Keytruda. Her forth got postponed because her liver enzymes shot up. She has been admitted to hospital because it looks like she is dehydrated and has an infection. She has lost well over two stone in weight and hardly eats anything because she has lost her appetite. Her oncologist has now brought her scan forward to see if the treatment is doing anything and if not they will look at a different option. I guess what I’m asking is can the treatment still be working even though she looks so poorly and could all of this stem from her lack of food and water?? What will be the next steps if the treatment hasn’t done anything or the cancer has gotten worse? Is a scan after only 3 rounds of treatment long enough to even tell? Any answers you can provide would be really helpful as I’m struggling at the minute x

  • Hello Faye01

    Thank you for your post.

    I am sorry to hear that your mum has been diagnosed with metastatic bladder cancer. This must be a very difficult time for you and your family, particularly with her recent admission to hospital due to dehydration and infection, alongside her weight loss and reduced appetite.

    Unfortunately, only your mum's medical team, who know her full medical history and how she has responded to treatment so far, can tell you how effective the treatment has been. It is possible that the treatment is working and that the dehydration and infection are contributing to her current symptoms. However, as we are not involved in your mum's care, we cannot say this with certainty, nor can we predict what the next treatment options might be if the current treatment is no longer effective.

    I appreciate that this uncertainty can be very difficult to cope with.

    What I can say is that it is not unusual for scans to be carried out after three cycles of treatment. These scans help doctors assess how well the treatment is working and whether it should continue as planned.

    I wonder whether, with your mum's permission, it may be possible for you to speak with a member of her healthcare team, such as her specialist nurse. They are often best placed to explain the scan results, discuss treatment response, and talk through what may happen next.

    In the meantime, please do get back in touch if you have any further questions or concerns. If you would like to speak with one of our nurses directly, our freephone helpline is available Monday to Friday, 9am to 5pm, on 0808 800 4040.

    Kind regards,

    Jemma