Hello to you all.

this is my first post on here . I’m the wife and carer for my husband . We are 76 yrs of age an until recently . These last few weeks Allen has been out on targeted cancer treatment for enlarged spleen due to white cell count over crowding in spleen . He has a 18 cm increase to spleen size in 3 months. He has been on Zanubrutinib for a month now and white cells still climbing. Main probs atm are waking up with really bad head aches. I mean like thunderclap head aches. Feeling sick and head bombed. We think this maybe a side effect to TCD. The spleen isn’t painful unless pressed. Husband has had non symptomatic CLL 3 yrs . Watch and wait treatment until this last month. What can we expect now as to treatment for spleen? Radiology or Slpeenectomy  or something else? Thank you for reading my post and just wondered if anyone reading this knows of this problem from themselves or a professional on line to advise.