Severe mental health problems post-chemo

I’m 9 months post radical radiotherapy and interval chemo with oxaliplatin for rectal cancer (clear now).

During the Oxaliplatin regime I started feeling extremely depressed/ mentally unwell.

9 months on, despite seeing psychiatrist and trialling a few antidepressants, and forcing myself back to various daily activities including my part time job, I am still seriously mentally unwell.

It’s like I’ve had a complete personality transplant. I’m now almost constantly extremely low in mood, cry all the time regardless of what I’m thinking about, have lost all the good and positive aspects of my personality, my mental function is relatively poor, struggle to cope with the most basic things, have sleep problems, and more..

My mental health professionals are trying to manage / help me from the perspective of post-cancer and cancer treatment anxiety and depression and trauma, but it’s not helping..

I deep down feel like the actual chemotherapy has seriously affected the inner workings (neurotransmitters, regulatory systems etc) of my brain.

I was wondering if there are any medical specialists that I could potentially see (privately if needed) who are knowledgeable and experienced with this type of issue?

Yours (very desperately), Jason

  • Hi Jason

    This is a rarely discussed topic in conjunction with cancer. While people whisper the Big C (cancer) they whisper even less the big MH (Mental Health) Im sure you are correct in your self diagnosis that it is likely your treatment that is contributing to your mental health problems. Literature on chemotherapy and immunotherapy is showing increasing reports of psychiatric and neurological problems from these treatments. I also feel that I am not the same person I was before starting treatment, and I now suffer anxiety over random things. Ive never suffered anxiety before treatment despite having cancer for the past 10 years. I dont suffer from depression though. Perhaps a referral to a Neurologist if you can get one may give you a better insight into some of your problems. I hope that other people will contribute to this thread you have started.

    Ed