My husband has glioblastoma. He had a craniotomy last October followed by radiotherapy and chemotherapy. In January he had 3 cycles of temozolomide but the MRI scan in March showed disease progression. He began PCV chemotherapy in April but after the first cycle had low platelets and then low white blood cells so the second cycle was postponed for 2 weeks and then given at a reduced dose.
He takes Keppra but remains seizure free and 2mg dextamethasone for speech problems.
My question is about the significant fatigue with the treatment. Have you any suggestions about how long this will last or any tips in dealing with it? In recent weeks, my husband’s language skills have deteriorated and he can often have difficulty in recalling place names etc. Can this improve? I didn’t know whether it was due to the tumour or the treatment and whether I should ask about Speech Therapy.
He has been put forward for a trial Citadel - 123 in London so we are waiting to hear about that.
Any advice would be gratefully received.
