Chronic or Acute

Am I right in thinking CLL will produce mature cells (right shift) and AML produces immature cells (left shift)? If so, and I have left shift cells, shouldn't I see a blood doctor quite quickly? Also I'm quite symptomatic and have been for about 5 months. My GP has said I may have CLL. I've had 4 FBC in the last 2 months all with TWCC OF 14. GP is monitoring me.

  • Hello Angiemo and thank you for posting,

    I am sorry to learn that you are having blood tests and symptoms that are causing you concern.

    In chronic leukaemia the white blood cells are almost fully developed, but are not completely normal. They still work, but not as well as they should do at fighting infection. The body makes too many of these abnormal white blood cells. AML (acute myeloid leukaemia) starts from the fast and uncontrolled growth of early myeloid blood cells in the bone marrow. 

    The GP has guidelines for when to refer someone urgently to the hospital on a suspected cancer pathway. If there was any concern, particularly of an acute leukaemia you would expect to be referred to see a haematologist( blood specialist) urgently. Although your white cell count is raised, it may not be high enough to refer you which is why the GP is monitoring you.

    If you are concerned do discuss this with your doctor and ask why they do not think you need to be referred.

    I hope this reply helps in some way.

    Jemma

  • Thank you for your reply. My GP thinks I  have CLL but is monitoring me, my kidneys are failing too. It was monitoring my kidneys that showed my white cells are in trouble too.