Secondary Breast Cancer

Hello

My wife has secondary breast cancer with mets in her bones and liver. She has been having chemo for 9 months but it isn't working. The liver tumour is growing 10mm every 12 weeks. We are approaching the 'lets stop the treatment' stage. My wife is 65, strong and wants to fight on. She deals well with chemo. 

I am now looking at the 'what else is there out there' situation. I have read very positive peer reviewed works regarding Ivermectin. Including PubMed.I would like to discuss it with her oncologist but would like as much info as possible. 

Can you help/guide me. 

thank you

  • Hello IslaMac and thank you for posting.

    I am sorry to hear about your wife's situation. That is incredibly hard to deal with and of course, you will want to try and find out what you can for her. Unfortunately, I am not sure we are going to be able to be much help in this case.

    As a research charity, we cannot offer medical opinions about whether certain treatment drugs suit your wife's situation. However, I am aware that this drug is not currently licensed as an anti-cancer drug, but is used as an anti-parasite treatment. No evidence-based research or clinical trials exist to prove Ivermectin is effective as an anti-cancer medication. Without substantial evidence from large-scale clinical trials in human cancer patients, drugs are generally not recommended or available. We have more information on alternative therapies if helpful to read.

    We usually suggest that if people are interested in trials they discuss this with their specialist as they are often aware of trials that are going on. There is information about taking part in trials and a clinical trials database on our website, which you can look at. This lists the trials that we are aware of and have permission to put on the website.

    Almost all clinical trials must have a medical referral from their doctor to the doctor running the trial. If you and your wife see a trial on our database that you are interested in, you will need to discuss it with her doctor or cancer specialist. We suggest you print off a copy of the information and take it along to her appointment.

    All trials have very strict entry requirements. So she must match these to be able to take part. If it looks like an appropriate trial, the doctor can then send a referral to the doctor running the trial at your nearest participating centre.

    Our trials database has the details of most of the current trials that we are aware of and have also had permission to include. Unfortunately, it isn't comprehensive as there may be trials we don't know about or haven't been allowed to include. The National Institute for Health and Care Research (NIHR) has a database on its website called Be Part of Research.  There are other trial databases, such as the ISRCTN (International Standard Randomised Controlled Trial Number) registry and a US trials database called ClinicalTrials.gov, which lets you search by country,  but both of these feed into Be Part of Research.

    If you would like a second opinion on your wife's treatment, do talk this through with her consultant as they know her cancer and her previous treatments and can help send appropriate information.

    Breast Cancer Now, the UK breast cancer charity, may have more resources if useful, and they also have a patient forum where questions can be asked.

    Please get back to us if you need any more information or support.  You may find it helpful to talk things through with one of the nurses on our helpline.  The number to call is Freephone 0808 800 4040 and the lines are open from 9 am till 5 pm, Monday to Friday.

    Take care,

    Sarah