Test for Family members

Hi. Im trying to find out if there is a test you can have to see if cancer is a high risk within a family. My brother has just been diagnosed and there have been other family members who have passed away from cancer. My son is now a bit concerned and asked if there was any sort of test you could get. Can anyone help?

  • Hello I'm sorry to hear about your brother being diagnosed,yes you can have a genetic testing I had it done as I have lost a lot of family members,speak to your doctor hopefully he can help.

  • At our practice you fill in a form which GP then considers. It probably varies depending on practice.  

    Here is some more information from cancer research

    www.cancerresearchuk.org/.../genetic-testing-for-cancer-risk

    I personally decided against genetic testing when I realised that whether or not I had the faulty gene wasn't going to change my behaviour in the future as I was too scared to undergo preventative surgery (even if I were fit enough to do so) and I had already made some other lifestyle changes and was subject to monitoring. As for my children, given a specific risk on their father's side a negative result for me would not have helped them – they are old enough to make their own decision to have testing (or not).  I realised the reason I wanted to know was more for my children's sake than my own. 

    People vary a lot in the choice they make about genetic testing and, in order to make that choice, it helps to consider both why you want to know and how it would change things for you if you did.

  • Hello and thanks for your post,

    When cancer is in the family, people often assume that this greatly increases their risk of developing it, but this isn't necessarily so. Although the genes we inherit may influence our risk, this may not be by very much. No one is risk free and the risk of cancer increases for all of us as we get older. This is quite a complicated topic and it might be useful to look at our section explaining genes and inherited cancer risk at this link

    Cancer is described as a genetic disease because it is caused by mistakes or faults in the genes of in a single cell. But in most cases of cancer, these gene faults develop over someone's lifetime and are not inherited. Faulty cancer genes can be passed from one generation to the next, but they are uncommon.

    Genetic testing is only usually offered to people with a strong family history, as this predicts who is most likely to have inherited a cancer gene fault.

    If you have concerns about your family history the best thing to do would be to make a list of the members of the family that have been affected by cancer and the age that they were diagnosed and then discuss this with your GP. If your GP feels that this that you do have a strong family history they may consider referring you to a genetic clinic.

    It is also important that we do what we can to prevent cancer and indeed 4 out of 10 cancers can be prevented by leading a healthy life style. Have a look at the information on our website here

    We do have screening service in our country but it would be very difficult at this present time to test for all cancers.  Have a look at our information on what screening programmes we have here

    If you or your son would like to ring and discuss any of this then you are more then welcome to do so.  You may find it helpful to talk things through with one of the nurses on our helpline.  The number to call is Freephone 0808 800 4040 and the lines are open from 9am till 5pm Monday to Friday.

    Best Wishes,

    Catherine

  • Nurse Catherine has given you a comprehensive response.

    In short, it depends on the type of cancer. A small number of cancers are caused by genetic defects but far more are caused by lifestyle issues. My Mum used to list all the people on her side of the family who had died of cancer and say it ran in her family.
     

    As a cheeky teenager, I used to point out that without exception they'd all smoked over 30 a day, were all obese or at least heavily overweight and that most of them were also heavy drinkers! 

    She died of cancer aged 70 and never did stop smoking until diagnosed at stage 3. 
     

    It wouldn't hurt to ask your GP but be prepared for some lifestyle questions.

     

    Best wishes

    Dave