Hi, 

I hope I may be able to help you out here, a ca125 blood test Is what they do sometimes to look for any early signs of cancer it's a protein that's in the blood. 

A CA 125 test measures the amount of the protein CA 125 (cancer antigen 125) in the blood.

This test may be used to monitor certain cancers during and after treatment. In some situations, the test may be used to look for early signs of ovarian cancer in people with a very high risk of the disease. Please don't think this means it's cancer as 

A CA 125 test isn't accurate enough to use for ovarian cancer screening in general because many conditions can increase the level of this protein.

Conditions that can cause an increase in CA 125include many that aren't cancerous, such as menstruation and uterine fibroids. Certain cancers may also cause an increased level of CA 125, including ovarian, endometrial, peritoneal and fallopian tube cancers.

Why it's done

Your health care provider may recommend a CA 125 test for several reasons:

To monitor cancer treatment. If you have ovarian, endometrial, peritoneal or fallopian tube cancer, your provider may recommend a CA 125 test on a regular basis to monitor your condition and treatment.

But such monitoring hasn't been shown to improve the outcome for those with ovarian cancer, and it might lead to additional and unnecessary rounds of chemotherapy or other treatments.

To screen for ovarian cancer if you're at high risk. If you have a strong family history of ovarian cancer or you have an inherited gene that increases the risk of ovarian cancer, your provider may recommend a CA 125 test as one way to screen for this cancer.

Some providers may recommend CA 125testing combined with transvaginal ultrasound every 6 to 12 months for those at very high risk.

However, some people with ovarian cancer may not have an increased CA 125 level. And no evidence shows that this screening decreases the chance of dying of ovarian cancer. An elevated level of CA 125 could prompt your provider to put you through unnecessary and possibly harmful tests.

To check for cancer recurrence. Rising CA 125 levels may indicate that ovarian cancer has come back after treatment. Regular monitoring of CA 125 has not been shown to improve outcomes for those with ovarian cancer and may lead to additional and unnecessary rounds of chemotherapy or other treatments.

If your health care provider suspects that you may have ovarian cancer or another type of cancer, you may undergo additional tests. Other tests that may be helpful in evaluating these cancers include a transvaginal or pelvic ultrasound, serum human epididymis protein 4 (HE4), CT, and MRI. A procedure to remove a sample of cells for testing may be needed to confirm the diagnosis.

Hope this helps you a little bit more 

Hi thankyou for your reply,

my aunt who is 63 has been bleeding very heavily since July last year, she is post menopause and her last period was 10 years ago, she was referred originally on a 2ww to urology and subsequently had an ultrasound and cystscopy procedure but then the hospital re-referred her to gynaecology on another 2ww, she then had an ultrasound with transvaginal scan, followed by hysterscopy biopsy, smear and bloods, they found at that appointment that she had some cysts, polyp and free fluid in the pouch of Douglas, bloods were high ca125 was 246, which then generated a urgent request for the CT scan last Sunday, the polyp removal was unsuccessful as her bleeding is very bad and will have to now be rescheduled, this all has happened within the last 2-3 weeks so moved very fast, do you know how long they may come back with results from her CT ? And the free fluid in the pouch of Douglas n high bloods could these be connected?

Once again thankyou for your time 

Hi thankyou for your reply,

my aunt who is 63 has been bleeding very heavily since July last year, she is post menopause and her last period was 10 years ago, she was referred originally on a 2ww to urology and subsequently had an ultrasound and cystscopy procedure but then the hospital re-referred her to gynaecology on another 2ww, she then had an ultrasound with transvaginal scan, followed by hysterscopy biopsy, smear and bloods, they found at that appointment that she had some cysts, polyp and free fluid in the pouch of Douglas, bloods were high ca125 was 246, which then generated a urgent request for the CT scan last Sunday, the polyp removal was unsuccessful as her bleeding is very bad and will have to now be rescheduled, this all has happened within the last 2-3 weeks so moved very fast, do you know how long they may come back with results from her CT ? And the free fluid in the pouch of Douglas n high bloods could these be connected?

Once again thankyou for your time