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2,866 Views 2 Replies Last post: Feb 21, 2013 8:50 AM by Biscuit RSS
Biscuit 31 posts since
Oct 3, 2012
Currently Being Moderated

Feb 20, 2013 8:21 AM

PCV chemo - side effect help

Hello everyone,


I haven't posted for a few months but I have been lurking a bit. I'm after a bit of advice today -

My other half is currently undergoing chemotherepy for a GBM brain tumour and is being given PCV - via drip on the 'first day' of the cycle and then Procarbzine tables for 8 days after (or something like that).  In the last cycle he began suffering from itching and a blotchey hives type rash. Of course we approached his consultant and the chemo ward for advice and they told us to get some priteaze (spelling?) which is an antihistamine to try and reduce the symptoms. This worked and they prescribed him some for the latest cycle.  However it's effictiveness seems to be reducing a bit and last night he had an awful night with the itching and discomfort and ended up having to take the priteaze tablet early to try and sleep.  Apparently you should only take one a day.


Has anyone else (or their loved ones) experienced anything similar and is there anything we can do at home? I have tried damp cool towels before and it didn't really do much.


I guess I am looking for a bit of reassurance that this is nothing to be concerned about.  The consultant said it is a common side effect but I just found it odd that he's developed it so far into the treatment (we've just had *hopefully* the last cycle in 6 months for a while).  Does the body build up a resistance to chemo and is this the way it is showing it?


Sorry for all the questions - I know you will all understand the lost and helpless feeling you get with this sort of thing.


Biscuit xxx

jules54 3,284 posts since
Sep 23, 2012
Currently Being Moderated
1. Feb 20, 2013 3:21 PM in response to: Biscuit
Re: PCV chemo - side effect help



Have to say that my husband's oncologist did explain that any side effects could happen at any time during the course of treatment and that as the chemo builds up in the body different problems can surface.  Though my husband had terrible sickness and the  chemo was stopped after just three sessions, his hair did not start to thin until the last session and his hearing was also affected after the 2/3 sessions (he still has tinnitus and hearing loss which can take some months to clear).  If the itching is not now being helped by the piriteze it would certainly be worth giving his support team another call as they may be able to change to alternative or change dosage. Maybe calamine lotion  could prove a help though would not use anything over the counter without referral as its difficult to know what and what not to use during chemo.  Not sure if this is re-assuring for you. It is very frustrating watching the side effects and  not  being able to contribute to making your other half better isn't it?  Hope the treatment does its job and these rotten side effects soon stop. Jules54

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