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I have just started Xeloda 2,300mg to take twice daily (4.600 in total) for stage 3 colon cancer as an adjuvant treatment after successful surgery in November.
Worried about potential side effects. But realise that not everyone gets them. Would be interested to know how anyone takeing this as a single agent find it?
Welcome to Cancer Chat. There are some very kind and helpful people here. I hope some of them will have experience of this drug and will be along to chat to you before long.
I am just starting round 7 xeloda with good results, had 4 lots of iv chemo without success, but this stuff has shrunk my original breast lump to less than 12mm so much so that they are going to operate to remove on friday and it has shrunk so much that theyhave had to put a clip on it so that they can find it in the operation.My lymph nodes have stayed the same so they are having to be taken away also. It is a bit of a regime to take, but I am so glad that i perservered with it.
Please, please make sure you moisturise your whole body daily and pay particular attention to your hands and feet day and night and drink plenty of water, I hvent rested like I should do but that is just me. I didnt have the quality of life with the iv stuff but I have with Xeloda.I have even managed to go back to work whilst taking it. Im going to be off again for a few months as having the op on friday, 6 weeks recovery and then radiotherapy. It has been a hard journey but the Xeloda has given me more freedom and a quality of life. i just hope that it has all been worth it on friday. I hope you have success with it too.
I was a rare case (also with stage 3 Colon Cancer) but was only on Xeloda for 4 days before chest pains forced it to be stopped. I am sure there are many hundreds, if not thousands that take Xeloda successfully however my advice to you is if you get any unusual pains then use the number they tell you to ring. I believe that for any standard side effects they tell you to ring your hospital but for chest pains you ring 999. Do not feel bad, I spent the 10 minute ride in the ambulance apologising to the paramedic in the back with me however they really don't mind. As he said it is the drunks on a Saturday night with a bruised knee that gets their goat not the cancer patient with chest pains.
I am glad you have found us on here - please continue to let us know how you get on as it will help others to monitor your progress.
Im a breast cancer patient and was on this chemo as part of a clinical trial back in 2007, (Tact2 trial) the regime i was allocated from the Marsden was"Arm 4" which was split into 2 seperate parts this was 4 x Epi accelerated followed by 4x Xeloda, when i was on Xeloda. I was taking 4,000 mgs a day, i think the doses are calculated on a persons body size/weight ect, and like you the tabs were split into 2 seperate daily doses,
Xeloda is quite a kind chemo in that it doesnt cause any hair loss, and as it is taken orally it doesnt cause any problems with your veins ect , i was told by my onc to try and make sure i took the tabs at even intervals 12hrs apart ,and to to make sure i took them "after food "eating at least 30mins before taking, i found that just some toast and cereal was enough to avoid any stomach/digestive probs as sometimes it was hard for me to eat a bigger meal at the times i was taking the tabs because of the spaceing out the doseages ,
The main potencial problems SEs wise apart from fatigue and a drop in blood count, which is common with all chemos, can sometimes be sore hands and feet , though this doesnt always affect everyone, i was advised by my oncologist to keep moisturising my hands and feet daily with either E45 cream or another very good moisturiser called "udderly smooth" which you can buy online from places like Amazon,udderly smooth is used mostly for cows udders ,but is also a brilliant moisturiser for people and i still know lots of breast cancer ladies who use udderly smooth when on Xeloda as it realy helps to stop the hands and feet from cracking and becomeing sore.
Luckily for me, i didnt suffer wth any real problems with any soreness of my hands/feet so definately the moisturising often and daily realy did help.
All in all for me i can say i found this chemo quite kind compared to others and also because Xeloda is a very selective chemo and targets specificaly only "cancer cells" and not our normal cells i found for the most part i was able to carry on with my life as near normal as possible.
Xeloda realy is a very good chemo, and i know lots of breast cancer patients who have been on this chemo for quite some time and have had very good results with it, there is also lots of info on Xeloda on the Xeloda.com website which may also be of help to you with any other questions you may have.
Good luck to you tabby and all the very best to you .
I had Apr surgery Sept 27/2011. I started Xeloda tabs 4000mgs daily 22/Nov for 2 weeks and then a week off.When I had my bloods done prior to getting my 2nd cycle of tablets my White platelet count was low(64) so I had to wait another week.Next blood test was ok so had my 2nd cycle.Today been to hospital and blood count low again(60) so again delayed a week.
I have been o.k.,just a bit tired and some diarrhoea,but no problems with hands or feet.Really hoping it stays this way.
When you read about the side effects some people have to endure,I feel very lucky.
Hope all goes well for you and you continue to post.Are you fully recovered from your surgery?
Hi All. Thanks for these replies..I feel much more reassured now. The unknown is so scary and when you read of the possible side effects, a 6 month course of treatment seems a nightmare. But so would be the risk of not takeing the chemo.
I agree, the fact that hair loss isn't likely on this is a huge relief. But 4 days into the treatment and I am finding out I can get tired really easily if I try to do my usual activites..like going for a long walk or gardening!!
I had the op Nov 5th. Chemo started on 9 Jan. So I was fully recovered from the op before starting. That is why I found it hard as I was feeling so well!
That udderly creme is good..I brought mine from the hospital pharmacy £3.45 which is very reasonable.
Hi Tony. In answer to your post, I have been getting "mild" transient chest pains today, so rang the hospital and told to not take any more until seen by consultant tomorrow. I am hopeing it might just be a chest infection starting, but you have to report infections too so either way meds stopped temporarily.
Just wondered if you were OK after stopping Xeloda. Did you have to have an alternative chemo?